Chrome Kee Extension loses connection to New KeePass 2.43

If these problems only occur exactly after you upgraded KeePass, the most likely explanation is that you now have more than one KeePass installation and/or you removed KeePassRPC when uninstalling the older version.

It doesn’t appear as though there is anything fundamentally broken when using KeePass 2.43 so I would recommend looking at the above suggestion and the general troubleshooting guide rather than waiting for a “fix” that probably won’t arrive.